Fmri download

Parkes, J. Tiego, K. Aquino, L. Braganza, S. Chamberlain, L. Fontenelle, B. Harrison, V. Lorenzetti, B. Paton, A. Razi, A. MIT License. Nov 4, Packages 0 No packages published. Contributors 2. You signed in with another tab or window. Reload to refresh your session. The movie was preceded by 10s of rest, and participants were instructed to watch the movie and remain still.

Xue, G. Swaroop Guntupalli Florian J. Baumgartner Ayan Sengupta Falko R. Trepel C. Fox C. Tom S. Participants performed four different tasks within a single scanning session. Kaule Pierre Ibe Florian J. The total size of dataset is more than GB. Therefore files for individual modalities are made available below. Note, access to individual files is possible via openfmri.

To address this issue, we identified a right ventrolateral prefrontal region vlPFC whose activity correlated with reduced negative emotional experience during cognitive reappraisal of aversive images.

We then applied a pathway-mapping analysis on subcortical regions to locate mediators of the association between vlPFC activity and reappraisal success i. These results provide direct evidence that vlPFC is involved in both the generation and regulation of emotion through different subcortical pathways, suggesting a general role for this region in appraisal processes. Participants, with 3 similarly liked but differently flavored and colored beverages who were unable to detect maltodextrin participated in 6 exposure sessions during which each beverage was consumed 6 times consistently paired with one of 3 caloric loads 0, Swaroop Guntupalli Andrew C.

Besides, T1-weighted structural images and B0 field map were acquired as well. In particular, five task-related fMRI time series finger, foot and lip movement, overt verb generation, covert verb generation, overt word repetition, and landmark tasks were used to investigate which protocols gave reliable single-subject results.

Ten healthy participants in their fifties were scanned twice using an identical protocol days apart. Participants used their left index finger to respond to the presentation of a green box, and their right index finger to respond to the presentation of a red box.

In congruent trials the green box appeared on the left or the red box on the right, while in more demanding incongruent trials the green box appeared on the right and the red on the left. Fifteen BPD participants were receiving antidepressant medication and twelve were taking antipsychotic medication. Twenty age- and sex-matched controls were recruited from the community, however four were excluded due to technical issues during scanning, leaving sixteen controls.

Exclusion criteria for all participants included pregnancy, MRI contraindications, diagnosis of a psychotic disorder, previous head injury or current illicit substance dependence. Controls met the additional criteria of no personal or familial history of major mental illness. Ethical approval was obtained from the Lothian National Health Service Research Ethics Committee, and all participants provided written informed consent before taking part.

We used this task as it assesses neural responses to social exclusion, is known to activate a range of social brain regions and is amenable to reinforcement learning modelling. Participants were asked to imagine that the other players were real, as exclusion by both human or simulated players has been previously reported to be similarly distressing.

When the participant received the ball, they indicated which computer player they wished to throw the ball to with a button press. This was achieved by comparing the total duration of the previous trial, including reaction time, with the ideal trial time of ms: if this value was exceeded, a random jitter between 0 and ms was subtracted from the mean jitter time of ms; otherwise, the random jitter was added to ms. Jitter therefore varied between ms and ms. Mean block duration was 24s, with onsets denoted by the appearance of the cartoon figures following rest, and offsets by the conclusion of the final throw animation.

Blocks were randomized, and interleaved with 13s rest blocks. Within blocks, throwing events were jittered to permit event disambiguation for reinforcement learning analysis.

Changes in brain structure were assessed by means of high resolution T1-weighted anatomical imaging and voxel-based morphometry. Functional changes were measured using ASL fMRI and analyzed by a model-free approach, independent component analysis. Aminoff and Michael J. More concretely, along what visual and semantic dimensions are scenes encoded in memory? One hypothesis is that global spatial properties provide a basis for categorizing the neural response patterns arising from scenes.

In contrast, non-spatial properties, such as single objects, also account for variance in neural responses. We demonstrate that these dimensions may be better understood within the more general framework of associative properties. That is, across both the perceptual and semantic domains, features of scene representations are related to one another through learned associations.

Critically, the components of such associations are consistent with the dimensions that are typically invoked to account for scene understanding and its neural bases. Moreover, we find that the voxel-wise neural patterns arising from these associations are significantly correlated with the neural patterns arising from everyday scenes providing critical evidence whether the same encoding principals underlie both types of processing.

These neuroimaging results provide evidence for the hypothesis that the neural representation of scenes is better understood within the broader theoretical framework of associative processing. In addition, the results demonstrate a division of labor that arises across scene-selective regions when processing associations and scenes providing better understanding of the functional roles of each region within the cortical network that mediates scene processing.

Egger William E. Copeland Adrian Angold Kimberly L. As an exploratory analysis, we investigated whether distinct anxiety disorders differ in the patterns of this amygdala-prefrontal dysregulation.

Preschool symptoms of generalized anxiety, separation anxiety, and social phobia were assessed with the Preschool Age Psychiatric Assessment PAPA in the first wave of the study when the children were between 2 and 5 years old. The PAPA was repeated at age 6. We conducted functional MRIs when the children were 5.

Preschool generalized anxiety predicted less functional connectivity between the amygdala and dorsal prefrontal cortices in response to fearful faces. Finally, a history of preschool separation anxiety predicted less school-age functional connectivity between the amygdala and the ventral prefrontal cortices to angry faces and greater school-age functional connectivity between the amygdala and dorsal prefrontal cortices to angry faces.

Our results also provide preliminary evidence for the neurobiological differentiation of specific preschool anxiety disorders. Wager Jason T. However, it is unclear whether self-regulation primarily influences primary nociceptive and affective processes or evaluative ones.

In this study, participants engaged in self-regulation to increase or decrease pain while experiencing multiple levels of painful heat during fMRI imaging. Both heat intensity and self-regulation strongly influenced reported pain, but they did so via two distinct brain pathways. Self-regulation did not influence NPS responses; instead, its effects were mediated through functional connections between the nucleus accumbens and ventromedial prefrontal cortex.

This pathway was unresponsive to noxious input, and has been broadly implicated in valuation, emotional appraisal, and functional outcomes in pain and other types of affect. David Creswell Michael J. Tarr Adrian Nestor James K. Pattern analyses suggest that encoded memories were reactivated during the distractor task, and performance of the distractor task led to superior recall for the associate pairs, compared to a control condition in which no distractor task was performed.

No changes were found in the Salience Network SN , a surprising result as the network is involved in the modulation of emotional and fluid reasoning. Using a seed-based approach, we have now analyzed effects of modafinil on the functional connectivity FC of insular subregions.

Analysis of FC with resting state fMRI rs-FMRI revealed increased FC between the right posterior insula and the putamen, the superior frontal gyrus and the anterior cingulate cortex in the modafinil-treated group. Modafinil is considered a putative cognitive enhancer.

The rs-fMRI modifications that we have found are consistent with the drug cognitive enhancing properties and indicate subregional targets of action. Experimental runs each seconds long were separated by a 1. Each run consisted of two performance blocks 8 repetitions of a sequence paced by an auditory signal at a fixed rate of 1. Each run began and ended with a rest period of 36 seconds and 24 seconds, respectively.

Participants were instructed to ignore the meaning of the printed word and respond to the ink color in which the word was printed. Each condition was meant to elicit a certain level of attentional demand. Participants responded to ink color by pressing button under the index, middle, and ringe fingers on their right hand.

One button for each color red, green, and blue on an MR-safe response box. Task begins with a 1,ms fixation cross followed by the stroop stimulus for 2,ms. The interstimulus interval between successive trial starts was sampled from an exponential distribution, between 3 and 20 s with a mean of 4 s and a median of 3 s, in order to ensure accurate deconvolution of the hemodynamic response.

Conditions were pseudorandomized in an event related fashion. Stimuli were back projected on a screen located at the back of the MR bore with an MR safe projector. Participants used a mirror attached at the top of the head coil to view. This study using response time as a behavioral variable. Reconstruction was also used to identify the presented image among millions of candidates. Poldrack W. We also used psychophysiological interaction analysis independent seeded at vmPFC to identified the brain areas showing interaction with vmPFC over the course of training.

These findings highlight the importance of experience in development of biases in decision-making. The aim was to investigate and compare spinal and supraspinal activation patterns of identical mechanical stimulation before and after sensitization using functional spinal magnetic resonance imaging spinal fMRI. Testing was always performed in the area outside of capsaicin application i.

Results should help prioritize approaches for further in vivo studies on pain processing and modulation in humans. Subjects completed 14 rounds of route learning during which they viewed repetitions of the routes and learned to predict the destination of each.

After exiting the scanner subjects completed a picture test in which they were shown still images selected from the routes and were asked to identify the destination associated with each image. Two independent experiments were performed using different sets of routes. For understanding how different FNs overlap in the human brain and how the timecourses of overlapping FNs are modulated by cognitive tasks, we applied spatial independent component analysis sICA to functional magnetic resonance imaging fMRI data.

These data were acquired from healthy participants while they performed a visual task with parametric loads of attention and working memory. The scanning plane was off the AC-PC line rostrally at 20 degrees. The thin scanning slice and tilted scanning plane were used to reduce susceptibility-related signal loss at the basal forebrain Deichmann et al Each participant had three functional runs, and each run used a different task script and acquired volumes.

The order of scripts was counterbalanced across participants. However, no systematic data collection has so far been undertaken toward a fine spatial and systematic representation of mental functions. In order to attain to such a comprehensive atlas of brain responses, the Individual Brain Charting IBC project aims to provide a dataset that contains high-resolution multi-task fMRI data. These refer to a cohort of twelve participants performing many different tasks, yielding a precise mapping of the underlying functions, free from both inter-subject and inter-site variability.

Additionally, the dataset is complemented with high-resolution anatomical and diffusion images, pertaining to a fine anatomical characterization of these brains. Ordaz Charles F. However, the development of the interactions between reward and cognitive control processing are just beginning to be understood. Using event-related functional neuroimaging and an incentive modulated antisaccade task, we compared blood-oxygen level dependent activity underlying motivated response inhibition in children, adolescents, and adults.

Deconvolution methods followed steps delineated previously Ward, Briefly, our model consisted of two orthogonal regressors of interest for reward and neutral correct AS trials, as well as regressors for incorrect AS trials and all VGS trials.

Linear and non-linear trends and six motion parameters were also included as nuisance regressors. A unique estimated impulse response function i. The estimated impulse response function reflects the estimated BOLD response to a type of trial reward AS trial after controlling for variations in the BOLD signal due to other regressors.

We made no assumptions about the shape of the function. We specified the duration of the estimated response from the trial onset 0 seconds to 24 seconds 17 TRs post trial onset, a sufficient time window for the hemodynamic response to peak and return to baseline, which was defined as the jittered fixation periods between trials.

Subjects were scanned while completing a Theory of Mind localizer task, and while completing the moral judgment task. For each scenario, subjects saw a text-based version of the scenario, and rated its moral wrongness on a scale. Each scenario text was presented in 4 serial segments, comprising Background, Action, Outcome, and Intent.

Schouten, J. Ishai, A. Furey, M. Gobbini, M. Haxby, J. High-resolution T1-weighted spoiled gradient recall SPGR images were obtained for each subject to provide detailed anatomy 1. Stimuli were gray-scale images of faces, houses, cats, bottles, scissors, shoes, chairs, and nonsense patterns.

The categories were chosen so that all stimuli from a given category would have the same base level name. The specific categories were selected to allow comparison with our previous studies faces, houses, chairs, animals, and tools or ongoing studies shoes and bottles. Control nonsense patterns were phase-scrambled images of the intact objects. Twelve time series were obtained in each subject.

Each time series began and ended with 12 s of rest and contained eight stimulus blocks of s duration, one for each category, separated by s intervals of rest. Stimuli were presented for ms with an interstimulus interval of ms. Repetitions of meaningful stimuli were pictures of the same face or object photographed from different angles.

Stimuli for each meaningful category were four images each of 12 different exemplars. For each session participants arrived to the lab fasted 4 hours. In the pre-conditioning session, participants were trained on how to use the scales to rate overall intensity, sweetness, liking, and wanting. Then participants rated each of the non-caloric stimuli 3 times. Participants, with 5 similarly liked beverages who were unable to detect maltodextrin were then trained on the fMRI procedures.

Meanwhile a second experimenter prepared the subject-specific beverage assignments so that color, flavors and caloric load were counterbalanced across subjects. The participant was then scheduled for 5 exposure sessions during which each beverage was consumed 6 times. Following the exposure sessions, subjects returned for a post-conditioning session where they rated the 10 non-caloric beverages for sweetness, liking, familiarity and wanting as in the pre-conditioning session.

The task is described in more detail in: FitzGerald et al. Sequential inference as a mode of cognition and its correlates in fronto-parietal and hippocampal brain regions.

Smith, S. Frank, M. Behrens, T. The newly posted version contains the full set of onsets for all conditions. Savage W. Kyle Simmons Rick E. Ingram Alicia A. Clair Laura E. Marc Lebel Andrew S. Nencka Alexander D. Resting-state connectivity in seven healthy adult subjects was assessed using this sequence. Four echoes were acquired with a multiband acceleration of four, in order to increase spatial resolution, shorten repetition time, and reduce slice-timing effects on the ASL signal.

Seed-based and dual-regression approaches were utilized to analyze functional connectivity. Haxby Andrew C. Connolly Yaroslav O. Go to this page and download the appropriate AWS client for your operating system.

Once it has been installed, open a Terminal, navigate to the Desktop, and type the following:. For a video tutorial of how to download the data, click here. Andy's Brain Book latest.